1 Research Methodology--Introduction
a) Types of clinical study designs:
Case studies, observational studies, interventional studies
b)Designing the methodology
c) Sample size determination and Power of a study
Determination of sample size for simple comparativeexperiments, determination of sample size to obtain a confidence interval ofspecified width, power of a study.
a) Types of clinical study designs:
Case studies, observational studies, interventional studies
b)Designing the methodology
c) Sample size determination and Power of a study
Determination of sample size for simple comparativeexperiments, determination of sample size to obtain a confidence interval ofspecified width, power of a study.
2 Biostatistics
2.1 a) Introduction
c) Measures describing the
central tendency distributions- average, median, mode
d)Measurement of the spread of
data-range, variation of mean, standard deviation, variance, coefficient of
variation, standard error of mean.
2.3 Basics of testing hypothesis
a) Null hypothesis, level of significance, power of test, P value,
statistical estimation of confidence intervals.
b) Level of significance
(Parametric data)- students t test (paired and unpaired), chi Square test,
Analysis of Variance (one-way and two-way)
c) Level of significance
(Non-parametric data)- Sign test, Wilcoxan’s signed rank test, Wilcoxan rank
sum test, Mann Whitney U test, Kruskal-Wall is test (one way ANOVA)
Pearsonn’s and Spearmann’s correlation and
correlation co-efficient.
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